GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9921338 | 1 | rs8049173 | chr16:11436882 | C16orf75 | chr16:11343506-11445617:+ | 0.25 | 3.98 | 8.34E-5 | Vein graft stenosis in coronary artery bypass grafting |
| BLCA | cis | rs8049439 | 1 | rs8049439 | chr16:28837515 | EIF3C | chr16:28722782-28747052:+;chr16 | 0.26 | 4.68 | 3.97E-6 | Educational attainment;Inflammatory bowel disease (early onset);Educational attainment (years of education) |
| BLCA | cis | rs763014 | 1 | rs8054842 | chr16:672799 | WFIKKN1 | chr16:679239-684116:+ | 0.28 | 5.31 | 1.85E-7 | Height |
| BLCA | cis | rs9921338 | 1 | rs8055427 | chr16:11436883 | C16orf75 | chr16:11343506-11445617:+ | 0.25 | 3.98 | 8.34E-5 | Vein graft stenosis in coronary artery bypass grafting |
| BLCA | cis | rs8072100 | 1 | rs8065437 | chr17:45721653 | C17orf57 | chr17:45401142-45518675:+ | 0.26 | 5.63 | 3.58E-8 | Very long-chain saturated fatty acid levels (fatty acid 20:0) |
| BLCA | cis | rs8072100 | 1 | rs8065669 | chr17:45724996 | C17orf57 | chr17:45401142-45518675:+ | 0.25 | 5.58 | 4.51E-8 | Very long-chain saturated fatty acid levels (fatty acid 20:0) |
| BLCA | cis | rs7224737 | 1 | rs8070446 | chr17:40285879 | DHX58 | chr17:40253422-40264751:- | -0.25 | -4.56 | 6.82E-6 | Fibrinogen levels |
| BLCA | cis | rs8078723 | 1 | rs8070454 | chr17:38160754 | ZPBP2 | chr17:38024455-38034144:+ | -0.21 | -3.95 | 9.46E-5 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
| BLCA | cis | rs8071789 | 1 | rs8071789 | chr17:38006333 | ZPBP2 | chr17:38024455-38034144:+ | 0.41 | 8.18 | 4.36E-15 | Selective IgA deficiency |
| BLCA | cis | rs8072100 | 1 | rs8072100 | chr17:45674687 | C17orf57 | chr17:45401142-45518675:+ | -0.27 | -6.04 | 3.63E-9 | Very long-chain saturated fatty acid levels (fatty acid 20:0) |
| BLCA | cis | rs7224737 | 1 | rs8074708 | chr17:40286354 | DHX58 | chr17:40253422-40264751:- | 0.25 | 4.63 | 4.92E-6 | Fibrinogen levels |
| BLCA | cis | rs807669 | 1 | rs807669 | chr22:19154522 | SLC25A1 | chr22:19163095-19166301:- | -0.32 | -5.67 | 2.87E-8 | Metabolite levels |
| BLCA | cis | rs807669 | 1 | rs807670 | chr22:19154608 | SLC25A1 | chr22:19163095-19166301:- | -0.26 | -5.1 | 5.42E-7 | Metabolite levels |
| BLCA | cis | rs9900280 | 1 | rs8081267 | chr17:27763910 | CCDC55 | chr17:28443834-28513485:+ | 0.25 | 3.93 | 0.000101 | Mean platelet volume |
| BLCA | cis | rs732528 | 1 | rs8093534 | chr18:48368020 | MRO | chr18:48321491-48351754:- | 0.27 | 4.69 | 3.82E-6 | Entorhinal cortical thickness |